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Quote:Fauci warned that the Omicron variant appeared to be able to “evade” the protection of two initial doses of the mRNA-type Covid vaccines – Pfizer/BioNTech’s and Moderna’s – as well as post-infection therapies such as monoclonal antibodies and convalescent plasma. Omicron is spurring new fears as US infections begin to surge again, with infections currently still led by the highly-transmissable Delta variant that has dominated since the summer.
Covid news: Boris Johnson unveils booster plan; South African president tests positive – as it happened | World news | The Guardian

Quote:On Sunday, South Africa logged 37,875 daily new infections, data from the National Institute for Communicable Diseases showed - the highest daily tally yet, exceeding the previous record of 26,485 set during the peak of the third wave in July, Bloomberg reports.
Covid news: Boris Johnson unveils booster plan; South African president tests positive – as it happened | World news | The Guardian
  • From a couple of hundred infections to almost 38K in a matter of weeks..
Quote:Boris Johnson says that at least one patient has been confirmed to have died with Omicron in the UK - the first death recorded with that variant. Speaking during a visit to a vaccination clinic near Paddington, in west London, the PM says: "Sadly yes Omicron is producing hospitalisations and sadly at least one patient has been confirmed to have died with Omicron. "So I think the idea that this is somehow a milder version of the virus, I think that's something we need to set on one side and just recognise the sheer pace at which it accelerates through the population. So the best thing we can do is all get our boosters."
 
Covid boosters: Johnson warns of Omicron spread as first death confirmed - BBC News

Quote:Health Secretary Sajid Javid meanwhile warns the variant is spreading at a rate "that we've never seen before" with Covid
 
Covid boosters: Johnson warns of Omicron spread as first death confirmed - BBC News

Quote:The number of daily Covid infections in the UK has been estimated as being at 200,00, Sajid Javid has said as he warned omicron cases are going to “dramatically increase”. On Monday the UK Health Security Agency said the number of daily Covid infections had now increased to 200,000. The NHS’ Covid alert level was also raised to four, the highest possible level.
 
UK Covid cases running around 200,000 a day, Sajid Javid says | The Independent
  • Near panic in the UK..
Quote:These buybacks come after share prices have surged in a historic manner, following a historically reckless money-printing binge by the Fed and other central banks, and by historically reckless interest rate repression in face of red-hot and worsening inflation. But note how buybacks collapsed to $89 billion in Q2 2020 and to $102 billion in Q3 2020, after share prices had plunged. This was based on the corporate strategy of buying high to drive up share prices even further when they’re already high, and not buying when share prices are low. When prices are high, this is also when insiders are dumping their shares, as they’re now doing, and it’s that much more important for companies to buy back those shares that insiders are dumping.
 
Share Buybacks Surge to Record ahead of Potential 1% Tax: Companies Buy as Insiders Dump like there’s No Tomorrow | Wolf Street

Quote:Despite multiple technological breakthroughs in the fight to control COVID-19, twice as many people died from it in 2021 compared to 2020. The Omicron variant is a stark reminder that effective vaccines are merely the first step toward ending the pandemic. Until we establish a process to manufacture vaccines at scale and distribute them where they are needed, we will lack the collective capacity to curb this or any future pandemic.
 
Health Innovation for All by Mariana Mazzucato & Jayati Ghosh - Project Syndicate
Quote:In this report, we present live neutralisation titres against SARS-CoV-2 Omicron variant, compared with neutralisation against Victoria, Beta and Delta variants. Sera from day-28 post second-dose were obtained from participants in the Com-COV2 study who had received a two-dose COVID-19 vaccination schedule with either AstraZeneca (AZD1222) or Pfizer (BNT162b2) vaccines. There was a substantial fall in neutralisation titres in recipients of both AZD1222 and BNT162b2 primary courses, with evidence of some recipients failing to neutralise at all. This will likely lead to increased breakthrough infections in previously infected or double vaccinated individuals, which could drive a further wave of infection, although there is currently no evidence of increased potential to cause severe disease, hospitalisation or death.
 
Reduced neutralisation of SARS-COV-2 Omicron-B.1.1.529 variant by post-immunisation serum | medRxiv
  • Two dosis of vaccines isn't going to stop the spread of Omicron, although it might very well still stop most hospitalizations and deaths.
Quote:Mainland China has reported its first case of the highly transmissible Omicron variant in the northern city of Tianjin, posing what could be the biggest threat to date to the country’s zero-Covid strategy. The Chinese authorities reported on Monday that the Omicron case was detected on 9 December from an overseas returnee, who showed no symptoms on arrival. The patient is being quarantined and treated in a designated hospital. At the same time, the eastern province of Zhejiang has been battling a rise in new infections of the Delta variant in recent weeks.
 
Mainland China reports first case of Omicron coronavirus variant | China | The Guardian
Quote:High levels of previous exposure to three previous waves of Covid infection in South Africa may explain the relatively low levels of hospitalisation and severe disease in the current outbreak of the Omicron variant, rather than the variant itself being less virulent. The suggestion was made by vaccine expert Shabir Mahdi of the University of the Witwatersrand, who has led vaccine trials in the country, and warned that South Africa’s experience of Omicron might not be a reliable indicator for how the Omicron outbreak unfolds in other countries.
In a lengthy interview with the Global Health Crisis Coordination Center, Mahdi cited a recently completed seropositivity survey – the percentage of population who have already been infected – in Gauteng province, which has been at the centre of the Omicron outbreak, that suggested some 72% had experienced a previous infection of coronavirus.
 Coronavirus live: Omicron poses real threat, says Moderna chief; Pfizer says Covid pill near 90% effective | World news | The Guardian

Quote:Two doses of Pfizer/BioNTech’s Covid vaccine appear to have given 70% protection against hospitalisation in South Africa in recent weeks, according to a major real-world study on the potential impact of Omicron. The study released by South Africa’s largest private health insurance administrator, Discovery Health, which co-led the study with the South African Medical Research Council. It was based on more than 211,000 positive Covid test results from 15 November to 7 December, around 78,000 of which were attributed to Omicron. Two doses of the vaccine offered 93% protection against earlier variants, according to Pfizer and BioNTech. It also found two Pfizer doses provide 33% protection against infection.
 
Coronavirus live: Omicron poses real threat, says Moderna chief; Pfizer says Covid pill near 90% effective | World news | The Guardian
Quote:In the UK, Dr Paul Burton, chief medical officer at Moderna, has been speaking to MPs on the Commons science and technology committee. Burton said he expects data in the coming days to show how well the Moderna booster improves protection against the Omicron variant. He cautioned against claims, largely from South Africa, that the variant is causing milder disease, and warned that Omicron and Delta are likely to circulate together for some time. “I do not think Omicron is a milder, less severe version of the current virus,” he told the committee. He added: The idea it will push Delta out of the way and take over may occur in the future, but I think in the coming months these two viruses are going to co-exist, and Omicron, which I would maintain is actually a severe disease, will now infect people on a background of very, very strong Delta pressure.

It will also lead to a situation where individuals will become co-infected … which gives the opportunity for this virus to further evolve and mutate which is a concerning and worrying situation. We certainly don’t have to panic, we have many many tools at our disposal, we’ve learnt so much about this virus over the last two years, and we can continue to fight it, but I think Omicron poses a real threat. When you look at the data in SA about 15% of people who are hospitalised are in the intensive care unit, and while there’s variability, if you look back earlier in the year, at a time of delta surge in August, those numbers are about the same, 15%. So while the mortality rate we are seeing right now is mercifully lower, I think as a disease it is a very fit virus and it’s severe.
 
Coronavirus live: Omicron poses real threat, says Moderna chief; Pfizer says Covid pill near 90% effective | World news | The Guardian
  • And luckily some good news, for a change..
Quote:Pfizer Inc has said final analysis of its antiviral Covid-19 pill still showed near 90% efficacy in preventing hospitalisations and deaths in high-risk patients, and recent lab data suggests the drug retains its effectiveness against the Omicron variant, Reuters reports. The US drugmaker last month said the oral medicine was about 89% effective in preventing hospitalisations or deaths when compared with placebo based on interim results in about 1,200 people. The data disclosed on Tuesday includes an additional 1,000 people. Nobody in the trial who received the Pfizer treatment died, compared with 12 deaths among placebo recipients.
 
Coronavirus live: Omicron poses real threat, says Moderna chief; Pfizer says Covid pill near 90% effective | World news | The Guardian
Quote:And for the subsequent waves, we’ve seen other patterns that lead to underestimation of severity. First, that’s the story at the start of every big Covid wave. Young people, who have more robust immune systems, get most of the early cases because they are generally much more social as well as often less rigorous about self-protection. Second, hospitalizations and deaths trail infections. Third, for South Africa in particular, its population is young (average age 27 versus 37 in the US and over 40 in the UK), which will somewhat blunt worst outcomes. As we know, Omicron is mighty contagious, so even less severe cases with many more infection can well yield hospital system collapse, but the claim that Omicron ain’t all that bad is not proven in RSA:

Today’s omicron report from Denmark compares % of cases that require hospitalization for delta vs omicron. It is HIGHER for omicron, and most of Denmark’s omicron cases were just diagnosed, meaning insufficient time has passed to require hospitalization
 Omicron Cases Serious in Denmark and Overall Morbidity Picture Not Pretty Either | naked capitalism
Quote:Soaring Covid cases could cause major shortages across industry, hospitality and healthcare, ministers have been told, as rail companies cancelled services and Royal Mail said it was experiencing high staff absences. According to cabinet sources, Boris Johnson and England’s chief medical officer, Chris Whitty, said at a briefing that rising cases would be likely to affect businesses with mass worker absences. Whitty also told ministers to expect a “significant increase” in hospital admissions.
 
Expect mass staff absences and major shortages, UK ministers told | Coronavirus | The Guardian
  • With Omicron cases doubling every 2-3 days, here is another way it can reduce economic growth
Quote:There are now 14 people in hospital with Omicron in the UK, the House of Commons has been told. Previously, there were thought to be 10 people
 
Covid: Johnson to hold briefing as cases break record - BBC News

Quote:People lose a lot of protection against the Omicron variant of Covid three months after their second dose of the vaccine, England’s deputy chief medical officer says. Dr Tom Waite, who’s been answering Newsbeat listeners’ questions, says while you get “good protection” from doses one and two, it “wanes over time”. “With [the] Delta [variant] that became significant at about five to six months, with Omicron that becomes a significant drop in your protection from three months,” he says.
 
Covid: Johnson to hold briefing as cases break record - BBC News
Quote:Cornell University reported 903 cases of Covid-19 among students between December 7-13, and a “very high percentage” of them are Omicron variant cases in fully vaccinated individuals, according to university officials. The school’s Covid-19 dashboard was updated late Tuesday afternoon, accounting for the jump in case numbers reported. “Virtually every case of the Omicron variant to date has been found in fully vaccinated students, a portion of whom had also received a booster shot,” said Vice President for University Relations Joel Malina in a statement. The fact that this high a level of outbreaks is happening among young people, who have robust immune systems, including those who were boosted, is not a good sign at all. Remember that boosters were first authorized for the elderly and at risk
 
Cornell Goes Code Red, Cancels Most Campus Activities During Covid Spike with "Very High Percentage" Omicron in Fully Vaxxed | naked capitalism

Quote:The Omicron Covid variant has been found to multiply about 70 times quicker than the original and Delta versions of coronavirus in tissue samples taken from the bronchus, the main tubes from the windpipe to the lungs, in laboratory experiments that could help explain its rapid transmission. The study, by a team from the University of Hong Kong, also found that the new variant grew 10 times slower in lung tissue, which the authors said could be an indicator of lower disease severity.
 
Omicron found to grow 70 times faster than Delta in bronchial tissue | Coronavirus | The Guardian

Quote:Britain’s economy has suffered a sharp slowdown since the arrival of the Omicron Covid variant and activity is at its weakest since February when a full lockdown was in force, a report has shown. The monthly flash estimate of economic activity compiled by IHS Markit and the Chartered Institute of Procurement & Supply (CIPS) reported a marked impact on the service sector from a tightening of government restrictions and a more cautious approach by consumers.
 
Omicron causing sharp slowdown in Britain’s economy, figures show | Economic growth (GDP) | The Guardian
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